用低剂量CT成像对肺癌的查时间有好处
Yang Xie1, Yiyin Zhang1, Peng Zhang1
1Department of Respiratory Diseases, Henan Key Laboratory of Chinese Medicine for Respiratory Disease, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan; Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-construction by Henan Province & Education Ministry of P.R. China, Henan University of Chinese Medicine, Zhengzhou, Henan.
低剂量CT (LDCT) 的肺癌查显示有好处,但好处的时间有所不同. 这些发现表明,LDCT查可能不适合那些寿命有限的人.
科学领域:
- 肺部病理学 肺部病理学
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 低剂量CT (LDCT) 的肺癌查越来越受欢迎.
- 最低发达国家人群查的好处可能不会立即出现.
- LDCT查不太可能有利于寿命有限的患者.
研究的目的:
- 确定肺癌风险较高的个体从LDCT查中获益的时间 (TTB).
主要方法:
- 使用LDCT对肺癌查进行基于人群的随机对照试验的PubMed系统搜索.
- 使用国家肺部查试验 (NLST) 已建立的分析框架和四项试验的汇总数据来估计TTB.
主要成果:
- 分析包括四项试验,共有64,105名参与者.
- 在NLST中,为了预防一个肺癌死亡,需要在1.78年内对2000人进行查.
- 预防一个死亡需要2.87到8.87年的查每1000到200个人,分别.
结论:
- LDCT查的临床益处可能不适合寿命有限的个体.
- 将TTB估计整合到患者选择中可以帮助最大限度地提高LDCT查的好处.
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