通过深度学习增强的非侵入性检测肺高血压和子类型通过胸部X射线图,通过导管验证
Zhihua Huang1, Xiaolin Diao2, Yanni Huo2
1Center for Respiratory and Pulmonary Vascular Diseases, Department of Cardiology, Fuwai Hospital, National Clinical Research Center for Cardiovascular Diseases, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing.
Chest
|June 20, 2025
概括
应用到胸部X射线的深度学习模型在检测肺高血压 (PH) 和与先天性心脏病相关的肺动脉高血压 (CHD-PAH) 中显示出高准确性. 这些工具可以帮助早期诊断,特别是在资源有限的地区.
科学领域:
- 医疗成像中的人工智能
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
背景情况:
- 肺高血压 (PH) 是一种严重的疾病,需要可访问的诊断工具.
- 早期PH检测对于管理和干预至关重要,特别是在资源有限的环境中.
研究的目的:
- 评估深度学习 (DL) 模型在检测PH和CHD-PAH中使用胸部放射 (CXR) 的准确性.
主要方法:
- 在大型回顾性队列 (4,576名患者) 上开发和验证了DL模型 (CXR-PH-Net,CXR-CHD-PAH-Net).
- 内部和外部验证数据集包括RHC确认的队列.
- 使用AUC,灵敏度和特异性评估的性能.
主要成果:
- 在PH检测中,CXR-PH-Net实现了高灵敏度 (0.902) 和AUC (0.964).
- CXR-CHD-PAH-Net在CHD-PAH检测方面表现出强的表现 (AUC高达0.908).
- 模型显示在轻度PH病例中检测CHD-PAH的灵敏度很好.
结论:
- 使用CXR的DL模型显示出作为PH和CHD-PAH敏感查工具的希望.
- 这些模型可以促进早期检测和选,特别是在服务不足的地区.
- 为了更广泛的临床应用,建议在不同人群中进一步验证.
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