在非自杀性自伤中改变结构共变网络:对社会情感功能障碍的影响
1Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA; School of Psychology, Korea University, Seoul, South Korea.
NeuroImage
|June 20, 2025
概括
非自杀性自我伤害 (NSSI) 与大脑网络效率的改变有关,特别是在管理情绪的区域. 这表明,针对情绪调节和传染的有针对性的干预措施可以帮助NSSI患者.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 脑部成像 脑部成像
背景情况:
- 非自杀性自我伤害 (NSSI) 在青春期和青春期流行,与大脑显著发育和社会情绪压力相吻合.
- 在了解NSSI患者社会情感缺陷的神经生理基础方面存在差距.
研究的目的:
- 研究NSSI患者的结构共变网络 (SCN) 的变化.
- 探索SCN变化与社会情感功能障碍之间的关联,包括情绪失调和情绪传染.
主要方法:
- 结构共变网络 (SCN) 由皮层厚度数据构建,使用T1加权的MRI扫描对61名NSSI患者和62名健康对照进行了扫描.
- 用图形理论分析来评估全球和区域网络属性.
- 自我报告问卷测量了情绪失调和情绪传染.
主要成果:
- 与对照组相比,患有NSSI的个体显示全球和本地效率降低,全球聚类系数降低.
- NSSI组表现出右侧胰岛节点强度下降,中后带皮层 (mPCC) 中枢节点强度增加.
- 较低的insula节点强度与减少的积极情绪传染相关;较高的mPCC中心度与增加的情绪失调有关.
结论:
- NSSI与大脑网络组织效率较低有关,特别是在社会情感区域.
- 结果表明NSSI的潜在治疗目标,重点是增强积极的情绪传染和情绪调节技能.
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