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Updated: Sep 18, 2025

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Published on: July 25, 2013

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使用深度学习的高亲和度蛋白质结合宏循环的准确 de novo 设计

Stephen A Rettie1,2,3, David Juergens2,4, Victor Adebomi1,2

  • 1Department of Medicinal Chemistry, University of Washington, Seattle, WA, USA.

Nature chemical biology
|June 20, 2025
PubMed
概括

基于扩散的新型管道RFpeptides快速设计用于治疗蛋白质的宏环结合剂. 这种方法实现了针对不同目标的高亲和度结合剂,使得用于诊断和治疗的定制设计成为可能.

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