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Updated: Sep 18, 2025

Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry
12:08

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Published on: March 18, 2012

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对参与氨酸生物合成的弗拉依赖单氧化酶PhzO的研究

Yan-Fang Nie1, Sheng-Jie Yue1, Peng Huang1

  • 1State Key Laboratory of Microbial Metabolism, and School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China.

Microbial biotechnology
|June 21, 2025
PubMed
概括

工程flavin还原酶 (Fre) 提高了flavin依赖的单氧化酶PhzO的催化效率,从而提高了生物活性phenazine衍生物的产生. 这项研究确定了一种新型二基化氨酸,3,4-二基氨酸-1-碳酸酸 (3,4-OH-PCA),具有显著的抗癌特性.

关键词:
3,4‐二基胺-1-碳酸 (3,4‐OH-PCA) 的碳酸.有抗癌性质的抗癌性质.弗拉文还原酶 弗雷单氧化酶 PhzOO 的使用.纳的生物催化剂.杂乱的酶活性活动.

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