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Updated: Sep 18, 2025

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
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Fractionation for Resolution of Soluble and Insoluble Huntingtin Species

Published on: February 27, 2018

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亨廷顿病中活动依赖性批量内细胞增多的结果来自亨廷丁哈普洛因缺乏

Han C G Tan1,2, Robyn L McAdam1, Andrew Morton1

  • 1Centre for Discovery Brain Sciences, Hugh Robson Building, University of Edinburgh, Edinburgh, Scotland, UK.

Journal of neurochemistry
|June 21, 2025
PubMed
概括

亨廷顿病 (HD) 涉及由于失去野生型亨廷丁 (htt) 功能而导致突触囊泡回收受损. 在HD模型中,活动依赖性散体内细胞结核 (ADBE) 的这种功能障碍表明,Haploinsufficiency有助于神经退行.

关键词:
亨廷顿病就是亨廷顿病.细胞内分泌症 (endocytosis) 发生在细胞内.简单地说,这是一个简单的缺陷.这里是鼠标鼠标鼠标鼠标鼠标鼠标.在前突触时,会出现突触前突触.突触囊泡中的突触囊泡

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