常规36周扫描:预测长时间的新生儿重症监护室入院情况
A Arechvo1,2, E Demertzidou3, S Adjahou1
1Fetal Medicine Research Institute, King's College Hospital, London, UK.
概括
母亲因素,36周超声波扫描和分娩数据有助于预测新生儿重症监护室 (NICU) 长期入院的情况. 然而,超过40%的这些入院患者在出生前仍然无法预测.
科学领域:
- 孕产妇与胎儿的医学
- 新生儿重症监护室新生儿重症监护室
- 预测性诊断是一种预测性诊断.
背景情况:
- 预测新生儿重症监护室 (NICU) 长期入院对于资源配置和优化新生儿护理至关重要.
- 母亲的人口统计特征和病史是已知的风险因素,但它们对长期新生儿重症监护室停留的预测能力需要进一步调查.
- 第三个三个月的超声波发现和劳动/分娩数据对现有的预测模型的附加值尚未完全确定.
研究的目的:
- 评估母亲因素对长时间入院的NICU的预测性贡献.
- 评估36周超声波扫描结果在预测延长NICU入院的增加值.
- 确定母性特征,超声波数据和长时间NICU停留的劳动/分娩信息的综合预测性能.
主要方法:
- 一组107,762名单独怀孕的妇女接受了评估,包括病史,胎儿体重估计 (EFW) 和多普勒测量 (子宫动脉PI,动脉PI,胎儿中脑动脉PI) 在怀孕35-36周.
- 采用多变量后勤回归模型来分析母体因素,36周扫描结果和劳动/分娩数据对延长NICU入院的独立贡献.
- 检测率 (DRs) 和接收器运行特征曲线 (AUCs) 下的区域被计算出来,以比较不同模型的预测性能.
主要成果:
- 母亲因素如BMI,社会剥夺,试管婴儿受孕,慢性高血压,糖尿病和妊娠前明显预测了长时间的新生儿重症监护室入院 (AUC 0.606).
- 36周扫描结果,包括胎液指数和带/中脑动脉PI,改善了预测 (AUC0.637与母亲因素).
- 结合劳动和分娩数据 (分娩时的妊娠年龄,分娩方式,出生体重百分比) 进一步提高了预测 (AUC 0.709),达到 57.2% DR 在非产妇事件的10% FPR (AUC 0.790).
结论:
- 母亲因素,36周超声波结果,以及分娩数据独立地对预测长时间入院的NICU做出了贡献.
- 尽管有显著的预测性贡献,但超过40%的长期NICU入院在产前仍然无法预测.
- 这些发现凸显了NICU入院的多因素性质和产前预测的局限性.
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