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Updated: Jun 25, 2026

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针对纤维细胞激活蛋白α的基于蛋白质的放射性药物:对目前进展情况的回顾

Abdelrahman Homedan1, Darpan N Pandya1, Nicholas J Schnicker2,3

  • 1Department of Radiology, University of Iowa, Iowa City, IA, 52242, USA.

EJNMMI radiopharmacy and chemistry
|June 21, 2025
PubMed
概括

针对纤维细胞激活蛋白α (FAP) 的基于蛋白质的放射性药物显示出癌症诊断和治疗的前景. 虽然研究仍在进行中,但这种方法尚未达到针对FAP向治疗的全部潜力.

关键词:
抗体是对抗体的一种.抗体碎片的一部分.癌症 癌症 癌症 癌症纤维细胞激活蛋白质的激活蛋白质定子发射断层扫描 (PET) 是一种定子发射断层扫描.辐射疗法 辐射疗法单域抗体是一种单域抗体.单光子发射计算机断层扫描热浪学是什么意思 热浪学

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Enzyme-linked receptors are cell-surface receptors acting as an enzyme or associating with an enzyme intracellularly. They make excellent drug targets. Drugs can bind to the extracellular ligand-binding domain or directly affect their enzymatic domain and alter their activity.
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