埃索诺菲尔性纤维炎是一种表皮炎
Iago Pinal-Fernández1, José César Milisenda2, Albert Selva-O'Callaghan3
1Muscle Disease Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Montgomery, EE. UU.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, EE. UU..
概括
酸性膜炎是一种罕见的疾病,导致疼痛的组织加厚. 诊断涉及临床,实验室和活检的发现,用葡萄皮质激素作为标准治疗.
科学领域:
- 类风湿病学 类风湿病学
- 皮肤病学 皮肤病学
- 病理学 病理学 病理学
背景情况:
- 乙酸性膜炎 (EF) 是一种罕见的类似于硬化皮质的综合征,病因不明.
- 它呈现为肢体和干部的带和皮下组织的痛苦硬化和逐渐加厚.
- 关键的实验室发现包括外周性爱素,高甘球蛋白血症和红细胞沉积率的升高.
研究的目的:
- 总结埃索诺菲尔带炎的临床,实验室和组织学特征.
- 讨论差异诊断和诊断方面的挑战.
- 概述当前对乙酸性带炎的治疗方法.
主要方法:
- 诊断通过受影响皮肤的全厚形活检来确认.
- 组织学检查揭示了深层 Fascia 的炎症和加厚.
- 临床,实验室和组织学发现用于诊断.
主要成果:
- 酸性带炎涉及疼痛,渐进的带和皮下组织的加厚.
- 标志性发现包括外周性异osinophilia,高血糖球蛋白血症和升高的ESR.
- 组织学显示炎症和加厚的深层带.
结论:
- 乙酸性带炎的诊断依赖于临床,实验室和组织学证据.
- 没有建立通用诊断标准.
- 葡萄糖皮质类药物是标准的治疗方法,尽管在某些情况下会出现自发改善.
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