一个便携式视觉/电化学双模式生物传感平台,用于同时检测两个真菌毒素
1Department of Child Health Care, Children's Hospital of Nanjing Medical University, Nanjing 210008, PR China; School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, PR China.
Journal of hazardous materials
|June 21, 2025
概括
一个新的双模式生物传感器提供了便携式和灵敏的检测菌毒素,如zearalenone (ZEN) 和fumonisin B1 (FB1) 在食品中. 这种先进的平台结合了视觉和电化学方法,以改善食品安全分析.
科学领域:
- 分析化学 分析化学
- 生物传感技术的技术
- 食品安全科学 食品安全科学
背景情况:
- 菌毒素在全球范围内污染食品,造成严重的健康风险.
- 传统的检测方法往往是昂贵和复杂的.
- 需要快速,便携和准确的真菌毒素检测系统.
研究的目的:
- 开发一个便携式视觉/电化学双模式生物传感平台,用于同时检测菌毒素.
- 为了方便和敏感地检测zearalenone (ZEN) 和fumonisin B1 (FB1).
- 为多重真菌毒素分析提供现场部署的解决方案.
主要方法:
- 开发一种双模式生物传感器,集成距离读取和阵列电极.
- 使用aptamer识别来触发影响电化学发光 (ECL) 长度的阻抗和电压变化.
- 使用电化学阻抗光谱 (EIS) 进行精确的量化.
主要成果:
- 通过视觉和电化学模式实现ZEN和FB1的同时检测.
- 视觉模式的线性范围:0.1300 ng·mL−1,LOD:0.069/0.084 ng·mL−1.0 的线性范围:0.1300 ng·mL−1.
- 电化学模式的线性范围:0.001300 ng·mL−1,LOD:0.37/0.42 pg·mL−1.1. 电化学模式的线性范围:0.001300 ng·mL−1,LOD:0.37/0.42 pg·mL−1.
结论:
- 开发的平台将可视检测的便携性与电化学分析的灵敏性相结合.
- 这种双模式生物传感器为食品安全中的多重真菌毒素检测提供了有效的解决方案.
- 该技术为关键食品安全监测提供了可在现场部署的分析工具.
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