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Updated: Sep 18, 2025

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
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大型抑郁症中上腺素系统失联:短期SSRI治疗的影响

Shuting Chen1, Jinqiang Zhang1, Guowei Wu2

  • 1Department of Clinical Psychology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China; National Clinical Research Center for Mental Disorders, Changsha, Hunan 410013, China.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
|June 21, 2025
PubMed
概括

重度抑郁症 (MDD) 显示出一个不平衡的位置coeruleus-norepinephrine (LCNE) 系统连接,连接感官和多式上皮层. 这种在三个样本中观察到的模式,在埃斯基塔洛普拉姆治疗后没有得到改善.

关键词:
功能连接性的功能连接性.这是一个LC-NE系统.这里是Locus coeruleus的地方.大型抑郁症主要是抑郁症.静止状态的FMRI是指静止状态的FMRI.短期SSRI治疗的治疗方法

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