探索ERAP1和ERAP2中单核酸多态的关联与对多种免疫媒介炎症疾病的易感性

Sofie Jørgensen1, Trine Bertelsen1, Lasse Kronborg1

  • 1Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Dermatology and Venereology, Aarhus University Hospital, Aarhus, Denmark.

Human immunology
|June 21, 2025
PubMed
概括

ERAP1和ERAP2基因的遗传变异与免疫介导炎症性疾病 (IMIDs) 有关. 这项研究没有发现共享的遗传因素,但揭示了在牛皮患者中与HLA-C的特定单双型相互作用,影响IMID风险.

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