使用大型语言模型进行本体学丰富:应用词汇,语义和知识网络的相似性,用于概念的放置
Navya Martin Kollapally1, James Geller2, Vipina Kuttichi Keloth3
1Kean University, United States.
Journal of biomedical informatics
|June 21, 2025
概括
这项研究开发了一个自动化的管道来丰富本体学,特别是健康本体学的社会决定因素 (SDoH),使用大型语言模型 (LLM) 和PubMed. 基于LLM的方法成功地识别了比现有数据库更相关的概念,增强了本体学.
科学领域:
- 生物医学信息学 生物医学信息学
- 知识表示 知识表示
- 本体学 工程学 工程学
背景情况:
- 实体学对于域名知识表示至关重要,并且需要全面的域名视图以获得实用性.
- 实体学丰富是必要的,以纳入该领域的新概念和进步.
- 健康的社会决定因素 (SDoH) 领域需要对其知识表示进行持续更新.
研究的目的:
- 开发一个自动管道用于本体丰富,使用种子本体,一个大语言模型 (LLM) 和一个文本库.
- 应用并证明该管道在扩展SDoH本体学 (SOHOv1) 的有效性.
- 在其他领域建立一个通用化的方法论来丰富本体学.
主要方法:
- 使用现有的SOHOv1概念作为搜索术语检索了PubMed摘要.
- 使用GPT-4-1201从摘要中提取语义三重组,然后使用词汇,语义和基于知识网络的方法进行过.
- 将提取的三倍数与SemMedDB的颗粒度进行比较,并使用人类专家和本体学工具验证了结果.
主要成果:
- 扩展了SOHOv1 (173个概念,585个公理) 到SOHOv2 (572个概念,1542个公理),显著增加了概念和公理数量.
- 基于LLM的方法与从SemMedDB提取的概念相比,发现了更多的概念.
- 证明了SDoH域的自动化缩管道的可行性和有效性.
结论:
- 从PubMed摘要中成功提取了通过提示链接使用GPT-4-1201的语义三位数.
- 证明了GPT-4-1201提取的三倍数对SemMedDB的优越性,用于SDoH本体学丰富.
- 利用先进的搜索技术来识别概念,并通过专家评估确认概念质量,验证方法论的通用性.
关键词:
大型语言模型.丰富本体学的丰富天体学评估评估的存在学.这是一个SemMedDB数据库.语义上的 MEDLINE 线.语义 MEDLINE 数据库是一个数据库.寻找相似性的搜索健康的社会决定因素更多相关视频
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