自腐蚀微电解增强膜通风电活性生物膜用于抗生素和抗生素耐药性基因减少
Han Zhang1, Haotian Jiang1, Liuxiao Jin1
1State Key Laboratory of Urban-rural Water Resource and Environment (SKLUWRE), Harbin Institute of Technology, 73 Huanghe Road, Nangang District, Harbin 150090, PR China.
Bioresource technology
|June 21, 2025
概括
一个新的生物电化学系统增强了抗生素和抗生素耐药性基因的去除. 这种综合系统有效地使微生物失活,大大减少了废水处理中的有害污染物.
科学领域:
- 环境科学 环境科学
- 环境工程 环境工程
- 微生物学 微生物学
背景情况:
- 抗生素和抗生素耐药性基因 (ARG) 污染对环境和健康构成重大风险.
- 传统的废水处理方法往往不足以完全去除这些污染物.
研究的目的:
- 开发和评估一种新的三维生物电化学系统,用于增强抗生素和ARG的去除.
- 调查消除过程背后的机制,包括生物膜特征和微生物失活.
主要方法:
- 连接自我腐蚀的Fe/C微电极与膜通风的电动生物膜反应器 (IC-MAEBR).
- 分析阴极生物膜的组成 (芳香蛋白,二次结构) 和密度.
- 在不同的应用潜力下量化特定ARG (sul1, sul2) 和抗生素 (SMX) 降解率的减少.
主要成果:
- IC-MAEBR丰富了芳香蛋白质,并增加了生物膜中的α-螺旋到 (β-sheet + random coil) 的比率,从而提高了密度.
- 应用的电位和微电解通过宿主微生物无活化显著降低了硫1和硫2的丰度.
- IC-MAEBR显示出优越的SMX去除动力学,特别是在0.5V,在12小时内实现了快速降解.
结论:
- 集成的微电解和电活性生物膜系统 (IC-MAEBR) 有效地去除抗生素和ARG.
- 微生物无活化是减少ARG的关键机制.
- 这项技术为先进的废水处理提供了有前途的方法,以打击抗生素耐药性.
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