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相关实验视频

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An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
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选择性关节手术前后的阿片类药物消费模式

Melina Martinez1, Tracy Yep1, Sara Chung2

  • 1Specialty Clinical Pharmacy Programs, Kaiser Permanente Washington, Renton, Washington.

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概括

在关节置换手术后使用阿片类药物很常见,在手术前使用者的39%继续使用10-12个月后. 这凸显了在全膝关节整形术和全关节整形术患者中管理阿片类药物处方的战略的需要.

关键词:
关节质复原 关节质复原 关节质复原 关节质复原在阿片类药物阿片类药物.疼痛 疼痛 疼痛 疼痛疼痛管理 疼痛管理术后疼痛 术后疼痛 术后疼痛

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科学领域:

  • 整形外科手术 整形外科手术
  • 疼痛管理 疼痛管理
  • 公共卫生 公共卫生

背景情况:

  • 使用阿片类药物带来了成和过量服用等风险.
  • 全膝关节整形术 (TKA) 和全关节整形术是常见的可选手术.
  • 这些手术旨在减轻疼痛,但可能导致慢性阿片类药物使用.

研究的目的:

  • 在全关节关节整形术后分析阿片类药物使用模式.
  • 为了确定与持续的术后阿片类药物使用相关的因素.

主要方法:

  • 对8886名接受TKA或关节整形手术的患者的回顾性分析 (2018年3月至2023年5月).
  • 术前阿片类药物使用者定义为在手术前3个月内有≥2次阿片类药物处方的人.
  • 奇平方测试用于比较手术后10-12个月的阿片类药物使用情况.

主要成果:

  • 24%的患者被确定为手术前的阿片类药物使用者.
  • 39%的术前阿片类药物使用者在术后10-12个月继续使用阿片类药物,而非使用者的比例为9% (P <0.05).
  • 女性性别和接受TKA与持续使用阿片类药物的可能性更高有关.

结论:

  • 了解术后阿片类药物使用对于最大限度地减少过度处方至关重要.
  • 很大一部分患者,特别是手术前的阿片类药物使用者,在关节置换后很长时间继续使用阿片类药物.
  • 需要进一步的研究,包括多变量分析,以证实研究结果并为临床实践提供信息.