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通过调节YB1/SLC7A11介导的受体细胞中ferroptosis,PHGDH可以缓解DKD

Yinghui Wang1, Qingqing Zhang1, Shasha Lv1

  • 1Department of Nephrology, Multidisciplinary Innovation Center for Nephrology, The Second Hospital of Shandong University, Jinan, Shandong 250033, China.

Translational research : the journal of laboratory and clinical medicine
|June 21, 2025
PubMed
概括

糖酸脱酶 (PHGDH) 通过防止铁亡,保护糖尿病病 (DKD) 的损伤. PHGDH针对YB1稳定SLC7A11,减少细胞损伤和改善功能.

关键词:
DKD DKD DKD 的意思是什么铁化是铁化的一种.PFGDH是什么意思在 SLC7A1111 中.YB1 一个 YB1 一个

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