早期与晚期静脉血栓塞栓症预防在患有严重粗固体器官损伤的患者
Aryan Rafieezadeh1, Kartik Prabhakaran1, Anna Jose1
1Westchester Medical Center, New York Medical College, Valhalla, NY, USA.
Injury
|June 21, 2025
概括
对于体固体器官损伤 (BSOI) 患者的早期静脉血栓栓塞 (VTE) 预防是安全的,并且与晚期预防相比,可以减少死亡率,血栓栓塞事件和住院时间.
科学领域:
- 创伤外科 手术 创伤外科
- 血管外科 血管外科
- 关键护理医学 关键护理医学
背景情况:
- 患有体固体器官损伤 (BSOI) 的患者患有血栓栓塞事件的风险增加.
- 这些患者静脉血栓栓塞 (VTE) 预防的最佳时间正在研究中.
研究的目的:
- 为了比较早期与晚期VTE预防的效果,在接受非手术治疗的严重BSOI成年患者中进行早期与晚期VTE预防.
- 评估VTE预防时间对死亡率,非手术管理失败和血栓并发症的影响.
主要方法:
- 对严重BSOI的成年患者的2017-2019年TQIP数据的分析.
- 将患者分为早期 (≤48小时) 和晚期 (>48小时) VTE 预防组.
- 倾向性得分匹配 (PSM) 控制混变量,然后进行比较分析.
主要成果:
- 早期VTE预防与明显较低的死亡率 (2.1%对3.9%) 和较少的非手术治疗失败 (12.4%对16.6%) 相关.
- 接受早期预防的患者的深静脉血栓塞 (DVT) 和肺栓塞 (PE) 发生率降低,住院和重症监护室停留时间缩短.
- 后PSM分析证实,晚期预防与较高的死亡率相关,非手术管理失败增加,住院时间延长.
结论:
- 早期VTE预防对于BSOI患者来说是安全有效的.
- 在受伤后48小时内启动静脉瘤预防与改善患者结果有关,包括降低死亡率和缩短住院时间.
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