电心电图异常在左捆分支块和医院外心脏骤停中的异常
Niels Saaby Hald1, Johannes Riis2, Signe Riddersholm3
1Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Medicin, Aalborg University, Denmark.
特定的心电图 (ECG) 测量,包括QRS持续时间和JTc间隔,可以帮助识别患有左捆分支阻塞 (LBBB) 的患者,这些患者有较高的非医院心脏骤停 (OHCA) 风险. 这些发现有助于对LBBB患者进行风险分层和有针对性的干预措施.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 预防医学 预防医学
背景情况:
- 左捆支部阻塞 (LBBB) 是心血管风险的公认指标.
- 有效的风险分层对于管理LBBB患者至关重要.
研究的目的:
- 研究特定心电图 (ECG) 参数在预测LBBB.患者医院外心脏骤停 (OHCA) 风险方面的有用性.
- 确定可帮助LBBB患者风险分层的ECG标志物.
主要方法:
- 来自哥本哈根全科医生实验室 (2001-2015) 的注册表数据的回顾性分析.
- 识别首次LBBB心电图和提取各种心电图参数 (例如QRS持续时间,JTc,QTc间隔,心率).
- 基于中位数参数值和多变量考克斯回归的分层来评估与OHCA的关联.
主要成果:
- 对4644名LBBB病例患者的分析,随访时间中位数为35,113人年.
- 在OHCA风险和QRS持续时间>150ms,JTc持续时间>317ms之间发现了显著的关联.
- 多变量分析表明,QRS持续时间>150毫秒,QTc持续时间>464毫秒,JTc持续时间>317毫秒,心率>72/分钟的OHCA危险比较高.
结论:
- 特定的心电图参数,包括QRS持续时间,JTc,QTc间隔和心率,与LBBB患者的OHCA风险增加有关.
- 这些心电图发现为改善风险分层和有针对性的干预提供了潜力.
- 发现了ECG异常的LBBB患者可能会从早期的专家评估中受益.
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