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精密生物制剂通过选择性地修改其肠道微生物组,以更好地应对肠道挑战,从而提高肉的生长性能
Cristiano Bortoluzzi1, Mick Watson1, Maria A Iuspa2
1dsm-firmenich, Animal Nutrition and Health, Kaiseraugst, Switzerland.
Poultry science
|June 22, 2025
概括
精密生物制剂 (PB) 通过促进有益的肠道细菌和短链脂肪酸 (SCFA) 生产来改善 brojler的健康. 这提高了生长性能和抗死肠炎 (NE) 的弹性.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 禽类营养 养 禽类营养
背景情况:
- 精密生物制剂 (PB) 是设计用于调节肠道微生物代谢的料添加剂,特别是增强短链脂肪酸 (SCFA) 生产.
- 在中,SCFA对胃肠道 (GIT) 的健康和功能至关重要.
- 死亡性肠炎 (NE) 对家禽的健康和生产力构成重大威胁.
研究的目的:
- 评估基于糖甘的PB对NE挑战的 brojler的 cecal微生物组和生长性能的影响.
- 为了确定PB补充是否可以通过影响微生物SCFA生产来减轻NE的负面影响.
主要方法:
- 进行了两项实验,涉及受NE挑战的肉.
- 鸟类补充了PB,并与对照组和被挑战的对照组进行了比较.
- 评估了微生物组分析,生长性能指标 (体重,料转换率),NE病变评分和死亡率.
主要成果:
- 补充PB显著改善了受挑战的鸟类的生长性能和料转换率.
- 观察到SCFA产生细菌 (例如,Faecalibacterium) 的相对丰度增加以及增强的酸和丁酸盐通路.
- 补充PB降低了NE相关的死亡率和病变严重程度.
结论:
- 基于甘氨酸的PB补充剂有效调节肠道微生物组,以增加 brojler的SCFA产量.
- PB增强了对肠道压力的弹性,改善了生长性能,并减少了NE的影响.
- 这些发现支持使用PB来改善家禽福利和可持续生产.
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