患有高级侵略性B2胆瘤的患者在CAP-Endostar组合疗法后取得了积极的结果
Min Zhang1, Jingjing Zhang1, Kelei Zhao1
1Department of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
The clinical respiratory journal
|June 22, 2025
概括
本病例报告详细介绍了一种侵入性胸腺瘤侵入主要静脉,被归类为Masaoka阶段IV. 用化疗和放射治疗治疗导致显著的瘤减少和持续的部分反应超过50个月.
科学领域:
- 在瘤学瘤学.
- 心血管医学 心血管医学
- 胸部外科手术 胸部外科手术
背景情况:
- 侵袭性胸腺瘤可以呈现为前端中质.
- 先进的Masaoka第四阶段胸腺瘤涉及血管入侵和血栓形成.
- 对于晚期胸腺瘤,手术并不总是适合的.
研究的目的:
- 报告一个先进的侵入性胸腺瘤病例,涉及广泛的血管.
- 为了说明马索卡第四阶段胸腺瘤的非手术治疗的疗效.
- 为了突出患有不可切割的胸腺瘤的患者的长期结果.
主要方法:
- 一个患有侵袭性胸腺瘤的患者的病例介绍.
- 诊断成像,以评估瘤的范围和血管入侵.
- 用六轮化疗和胸部放射治疗进行治疗.
- 临床和放射学随访50个月.
主要成果:
- 该患者出现了马索卡第四阶段的侵入性胸腺瘤,涉及左臂脑干静脉,右心室,上腔静脉和左内静脉.
- 在新辅助疗法后,瘤大小从72.43毫米减少到24毫米.
- 患者获得了部分反应 (PR),并在50个月的随访期保持无疾病,没有局部复发或远程转移.
结论:
- 化疗和放射治疗可以有效地管理具有血管入侵的高级侵入性胸腺瘤.
- 非手术治疗可以导致显著的瘤回归和长期的疾病控制.
- 这一案例表明,在 Masaoka 第四期胸腺瘤中,通过全身疗法和放射治疗得到了有利的结果.
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