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Updated: Sep 18, 2025

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
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KGiA:通过疾病意识知识图表增强来重新定位药物

Çerağ Oğuztüzün1, Zhenxiang Gao2, Hui Li2

  • 1Center for Artificial Intelligence in Drug Discovery, Case Western Reserve University, 10900 Euclid Ave, Cleveland, 44106, OH, USA; Department of Computer Science, Case Western Reserve University, 10900 Euclid Ave, Cleveland, 44106, OH, USA.

Journal of biomedical informatics
|June 22, 2025
PubMed
概括

本研究介绍了KGiA,这是一种使用反事实关系增强生物医学知识图 (KG) 的新方法. KGiA显著提高了药物重新定位的准确性,并确定了新的疾病候选药物.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.反事实关系是指反事实关系.药物重新定位是药物重新定位.微调的微调.基金会模型 基金会模型图形增强的图形增强方法图形拓学的图形拓学诱导性推理是一种诱导性推理.知识图是知识图.

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