GIT 27TLR4/Src/NOX2:,

Alessio Ardizzone1, Laura Cucinotta1, Giovanna Casili1

  • 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, Viale F. Stagno d'Alcontres 31, 98166, University of Messina, Messina, Italy.

概括

托尔类受体4 (TLR4) 抑制剂GIT 27在帕金森病 (PD) 鼠标模型中表现出神经保护作用. 它通过向TLR4/Src/NOX2通路来减少神经炎症和神经元损伤.

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