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Updated: Sep 18, 2025

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
10:49

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Published on: September 18, 2013

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阿利瑟蒂布通过抑制STAT3激活来抑制急性髓性白血病细胞生长

Pang-Ting Cheng1, Ho Lin1, Yu-Chiao Cheng1

  • 1Department of Life Sciences, National Chung Hsing University, No. 145 Xingda Rd., South Dist, Taichung 40202, Taiwan.

Toxicology and applied pharmacology
|June 22, 2025
PubMed
概括

阿利塞尔蒂布是一种欧罗拉激酶A (AURKA) 抑制剂,通过向pTyr705-STAT3信号,有效地减少急性髓性白血病 (AML) 细胞生长. 这项研究强调了阿利谢蒂布作为AML治疗的潜在治疗剂.

关键词:
在AML,AML就是AML.阿尔卡奥尔卡 (AURKA AURKA) 是一个艾利塞尔蒂布 (Alisertib) 是一个在STAT3中,我们可以使用STAT3.c-Myccc 的意思是我的

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