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证据表明,5-HT2A受体信号的有效性,而不是偏向的激动性,使色胺类迷幻药与非迷幻药区别开来

Aurelija Ippolito1, Sridhar Vasudevan1, Shaun Hurley2

  • 1University Department of Pharmacology, Oxford, UK.

British journal of pharmacology
|June 22, 2025
PubMed
概括

迷幻药物是无偏见的,部分的5-HT2A受体激动剂. 非迷幻药物以低效率而非连接物偏差来区分,这表明低信号效率解释了它们的非迷幻性质.

关键词:
5HT 5HT 的使用方法.5-HT2A受体的受体是什么在Gq和β-arrestin2信号传输中.有偏见的激进主义.迷幻类精神药物 迷幻类精神药血清胺 (serotonin) 是一种神经元.

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