对口腔潜在恶性疾病和口腔腔状细胞癌的诊断辅助和活检技术
Rachelle Wolk1, Alexander Ross Kerr1
1Department of Oral and Maxillofacial Pathology, Radiology and Medicine, New York University College of Dentistry, 345 East 24th Street, New York, NY 10010, USA.
Dental clinics of North America
|June 22, 2025
概括
诊断辅助有助于临床医生管理口腔潜在恶性疾病. 虽然不能取代活检,但自光和人工智能等工具有助于损伤评估和活检部位的选择.
科学领域:
- 口腔病理学 口腔病理学
- 生物技术是生物技术.
- 医学诊断 医学诊断 医学诊断
背景情况:
- 口腔潜在恶性疾病 (OPMDs),如白血病需要准确的诊断和管理.
- 早期发现和精确管理OPMD对于预防恶性转变至关重要.
- 目前的诊断方法严重依赖于活检和组织病理学,需要辅助来改善临床决策.
研究的目的:
- 审查目前和新兴的OPMD诊断辅助的应用.
- 讨论这些附加剂在损伤分类,活检部位选择和手术管理中的作用.
- 突出人工智能和液体活检等新技术在口腔癌诊断中的潜力.
主要方法:
- 对OPMDs的诊断附加剂的现有文献的审查.
- 讨论已建立的技术,包括组织自光,托卢伊丁蓝色染色和细胞病理学.
- 探索新兴技术,如共聚焦显微镜,液体活检,口腔微生物组测试和人工智能.
主要成果:
- 已建立的辅助工具有助于选病变和选择活检部位,但不能取代组织病理学.
- 新兴技术显示出对非侵入性或最小侵入性OPMD评估的希望.
- 最佳使用附加剂需要临床培训和经验.
结论:
- 诊断辅助是临床医生管理OPMD的宝贵工具,提高诊断准确性和患者护理.
- 整合人工智能和液体活检等新技术可能会彻底改变OPMD的诊断和管理.
- 需要进一步的研究和临床验证,以确定新兴的辅助器的最终作用.
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