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Updated: Sep 18, 2025

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
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计算模型预测了Rho-GTPase对Rap1b上的plexin受体GAP活性结合的功能,通过动态全变化

Nisha Bhattarai1, Lindsay Morrison2, Alexandre F Gomes2

  • 1Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio, USA.

Protein science : a publication of the Protein Society
|June 23, 2025
PubMed
概括

模拟了plexin-GTPase相互作用,揭示了与单个或多个GTPases结合时不同的动态和网络变化. 这些发现澄清了plexin信号传递机制.

关键词:
在GTPases中使用.动态的全ostery 的动态.-交换的交换方式分子动力学模拟,分子动力学模拟素跨膜受体的受体是什么蛋白质与蛋白质的相互作用

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