化学抗原受体的缓解 T 细胞-反射性扩散大 B 细胞淋巴瘤通过手术和 CD20 双特异性疗法解决
Vinny Lococo1, Luke Selby2, Rebecca Farmer3
1Department of Hematologic Malignancies and Cellular Therapeutics, University of Kansas Medical Center, Kansas City, USA.
Cureus
|June 23, 2025
概括
本病例报告详细介绍了一名患有耐火性扩散型大B细胞淋巴瘤 (DLBCL) 的患者,在CAR T细胞治疗失败后,通过手术解体和用epcoritamab维持治疗实现了缓解. 这突出了外科手术的重点.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 手术瘤学手术瘤学
背景情况:
- 扩散性大B细胞淋巴瘤 (DLBCL) 是最常见的非霍奇金淋巴瘤,对耐火病例的治疗选择有限.
- 化学抗原受体 (CAR) T细胞疗法为一些DLBCL患者提供了潜在的治疗方法,但化学免疫治疗后的复发率仍然很高.
- 对于在CAR T细胞治疗后复发的患者,没有确立的护理标准.
关键词:
cd20 生物特异性T细胞诱导疗法 (BTCE)仿真抗原受体 (汽车) T细胞疗法扩散型大B细胞淋巴瘤 (DLBCL)在dlbcl手术手术中.耐火的dlbclclcl 在这是一种外科切除术.瘤微环境 (TME) 是指瘤的微环境.更多相关视频
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