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老年人营养风险指数预测胰腺切除术的老年患者的术后结果:一种倾向性得分匹配分析
Xiaofeng Liu1, Kang Xue1, Yi Zhang1
1Division of Pancreatic Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, China.
Gland surgery
|June 23, 2025
概括
老年人营养风险指数 (GNRI) 预测了经过胰腺突切除术 (PD) 的老年患者的术后并发症. 具有营养风险的患者 (GNRI ≤98) 经历了较高的重大并发症和肺部感染率,这表明GNRI
科学领域:
- 老年医学 老年医学
- 外科手术的结果
- 营养评估 营养评估
背景情况:
- 老年营养风险指数 (GNRI) 是预测老年人手术后并发症和死亡率的工具.
- 胰腺双管切除术 (PD) 是一种复杂的手术程序,对老年患者来说具有显著的术后风险.
研究的目的:
- 调查老年营养风险指数 (GNRI) 与接受胰腺突切除术 (PD) 的老年患者的术后结果之间的关联.
- 为了确定GNRI是否可以预测PD后的主要发病率在这个患者群体中.
主要方法:
- 接受PD的老年患者 (≥65岁) 被纳入并分为有风险 (GNRI ≤98) 和无风险 (GNRI >98) 组.
- 倾向性得分匹配用于平衡基线特征并比较结果.
- 后勤回归分析评估了GNRI和主要发病率 (Clavien-Dindo ≥3b级并发症) 之间的联系.
主要成果:
- 处于风险的GNRI组显示严重并发症 (13.2%对5.4%) 和肺部感染 (17.8%对9.3%) 的比率显著更高,后倾向性得分匹配.
- 多变量分析确定了高风险的GNRI状态作为主要发病率的独立预测因素 (OR=2.698,P=0.04).
- 亚组分析表明高风险GNRI患者的手术前黄和更长的手术时间更高,尽管整体发病率/死亡率在风险层之间没有显著差异.
结论:
- 根据老年营养风险指数 (GNRI) 评估的营养状况,是老年患者胰腺突切除术 (PD) 后术后并发症的重要预测因素.
- GNRI可以帮助识别患有PD后不良结果风险较高的老年患者,并可能指导术后管理.
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