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Updated: Sep 18, 2025

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
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Published on: June 26, 2020

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在染色体末端连接过程中,PAXX和MRI的功能不同

Metztli Cisneros-Aguirre1,2, Felicia Wednesday Lopezcolorado1, Xiaoli Ping1

  • 1Department of Cancer Genetics and Epigenetics, Beckman Research Institute of the City of Hope, 1500 E Duarte Road, Duarte, CA 91010, USA.

iScience
|June 23, 2025
PubMed
概括

对于DNA双链断裂 (DSB) 末端连接 (EJ),PAXX和MRI并不是必不可少的. 然而,当DNA-PKcs或XLF被破坏时,PAXX有助于EJ,而MRI支持XLF介导的EJ.

关键词:
染色体组织组织分子相互作用分子相互作用.

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