形PEP呼吸对慢性阻塞性肺病患者运动表现的影响:单盲随机交叉试验
Nimit Kosura1, Aung Aung Nwe2, Chatchai Phimphasak2
1Department of Physical Therapy Prince of Songkla University.
概括
形正气压 (形-PEP) 提高了运动能力,并减少了COPD患者的呼吸短促. 这种方法有助于延迟动态高通胀,并增强运动耐力.
科学领域:
- 肺部康复治疗 肺部康复治疗
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 阳性呼气压 (PEP) 装置用于改善COPD患者的运动能力.
- 形PEP是一种特定类型的PEP,已经显示出潜力,但需要进一步研究最佳电阻选择及其对运动参数的影响.
- 有限的证据存在于个性化形-PEP设置及其对运动持续时间,动态膨胀 (DH) 和呼吸障碍的影响.
研究的目的:
- 评估个性化形PEP在改善COPD患者的运动能力,动态膨胀 (DH) 和呼吸障碍方面的有效性.
- 评估形PEP对炼时间和炼期间呼吸障碍的发生的影响.
主要方法:
- 一项随机交叉试验与中度至重度的COPD患者进行.
- 参与者使用形PEP设备进行了点行军练习,选择了电阻以达到最低要求的PEP水平 (不超过35cmH2O).
- 运动耐力时间,评估DH的运动结束启发能力 (IC) 和呼吸障碍 (修改的Borg尺度) 与假PEP条件相比较.
主要成果:
- 与假PEP相比,形PEP显著增加了运动耐力时间 (4.98分钟对3.99分钟,p=0.004).
- 运动结束时的吸气容量 (IC),DH的指标,在形-PEP (1.51 L与1.42 L相比,p=0.020) 显著改善.
- 呼吸障碍在与形PEP的隔离时间 (4对5,p=0.005) 显著降低,尽管在运动结束时没有显著差异.
结论:
- 个性化形PEP,设置在最低要求的水平,提高了COPD患者的运动能力.
- 形PEP有效地延迟了动态高通胀的发展和运动期间呼吸障碍的出现.
- 这种干预方法为改善COPD患者的运动耐受性和生活质量提供了有希望的方法.
相关概念视频
COPD: Management Using Bronchodilators and Corticosteroids
329
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
329
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.6K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.6K
Chronic Obstructive Pulmonary Disease
1.4K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.4K
Physiological Control of Respiration
3.7K
Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
3.7K
Pulmonary Function Tests
438
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
438
Factors Affecting Pulmonary Ventilation
1.7K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.7K


