怀孕期间母亲心脏功能的动态变化
Xiu-Juan Wang1, Ling-Ling Chen1, Ming-Huan Hong1
1Department of Cardiovascular Disease, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Frontiers in cardiovascular medicine
|June 23, 2025
概括
随着怀孕的进展,孕妇可能会经历心脏功能下降. 左心室全球纵向应变 (LV-GLS) 和P波到A
科学领域:
- 心脏病学 心脏病学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 怀孕期间的生理变化可能导致心脏功能障碍和不良结果.
- 左心室全球纵向应变 (LV-GLS) 和组织多普勒成像 (PA-TDI) 上的P波到A'持续时间是微妙心脏功能障碍的敏感标记.
研究的目的:
- 在怀孕期间调查心脏结构和功能的变化.
- 评估LV-GLS和PA-TDI在检测妊娠期间心脏变化的有用性.
主要方法:
- 一项前性横截面研究,涉及506名健康孕妇和172名非孕妇对照.
- 参与者被分为四组:怀孕早期 (T1),怀孕中期 (T2),怀孕晚期 (T3) 和非怀孕对照 (NPC).
- 分析了心声学参数,包括LV-GLS和PA-TDI,并使用多变量回归来确定影响因素.
主要成果:
- 左心室喷射分数 (LVEF) 在怀孕晚期下降,但仍在正常范围内.
- 绝对LV-GLS值显示,随着妊娠年龄的增长而逐渐下降 (P < 0.001).
- 与第一 (P = 0.012) 和第二 (P = 0.010) 三季度相比,PA-TDI 持续时间在第三季度显著更长.
- 妊娠年龄与LV-GLS (P = 0.027) 和PA-TDI (P = 0.014) 独立相关.
结论:
- 怀孕与左心室缩和腹功能下降的趋势有关.
- LV-GLS和PA-TDI是评估怀孕期间心脏功能微妙变化的宝贵工具.
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