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Updated: Sep 18, 2025

Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase
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Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase

Published on: April 23, 2019

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一个完全在的协议,以了解嗅觉受体-嗅觉受体相互作用

Bhavika Berwal1, Pinaki Saha2, Ritesh Kumar1,3

  • 1CSIR-Central Scientific Instruments Organisation, Chandigarh 160030, India.

ACS omega
|June 23, 2025
PubMed
概括

本研究介绍了一种in silico方法,用于预测嗅觉受体 (OR) 结构及其与气味剂的相互作用. 这种方法提高了对气味机制的理解,并有助于发现新的OR-香味剂对.

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Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
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