在行为干预的随机临床试验中注册的参与者寻求的信息
Kathryn M Ross1,2, Kelsey M Arroyo1, Megan A McVay3
1Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA.
Contemporary clinical trials communications
|June 23, 2025
概括
许多随机临床试验 (RCT) 参与者在注册之前在网上搜索信息,这可能会增加招生率. 报名后寻求信息对试验行为的影响很小.
科学领域:
- 临床研究 临床研究
- 行为科学 行为科学
- 医疗信息学 医疗信息学
背景情况:
- 参与者在随机临床试验 (RCT) 中寻求行为干预的信息尚未得到充分理解.
- 这项研究调查了RCT参与者中信息搜索的流行率和影响.
研究的目的:
- 探索行为干预RCT中信息搜索的普遍性.
- 为了确定人口特征是否影响信息搜索.
- 评估信息搜索对参与者知识和试验行为的影响.
主要方法:
- 对参与行为干预RCT的成年人进行了在线调查.
- 参与者回顾地报告了他们在入学前和后的信息搜索行为.
- 该调查还评估了所发现信息对其试验经验的影响.
主要成果:
- 37%的参与者搜索试验信息,28.3%的参与者在入学前进行搜索,17.4%的参与者在入学后进行搜索.
- 参与者寻求有关试验长度,条件,预期结果和补偿的详细信息.
- 招生前的搜索增加了招生概率;招生后的搜索对行为影响最小.
结论:
- 很大一部分参与者积极寻求有关行为干预RCT的外部信息.
- 在入学之前寻求信息可能会促进参与.
- 调查人员应考虑在线信息对参与者的期望和潜在偏见的影响.
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