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人类cDC1增强了CD226+终极耗尽的瘤透淋巴细胞的细胞毒性功能

Liam O'Brien1, Irina Buckle2, Ingrid M Leal-Rojas1

  • 1Cancer Immunotherapies Research Group, Mater Research Institute, University of Queensland, Translational Research Institute, Woolloongabba, Australia.

Oncoimmunology
|June 23, 2025
PubMed
概括

一种新的人性化小鼠模型允许研究瘤中耗尽的T细胞. 常规I型树突细胞 (cDC1) 通过终极耗尽的瘤透淋巴细胞 (TILs) 增强杀死.

关键词:
CD226 是一个CD226 CD226 是一个CD226人性化的小鼠.T细胞耗尽的情况cDC1 树突细胞黑色素瘤是一种黑色素瘤.

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