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Updated: Sep 18, 2025

A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human Cells
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A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human Cells

Published on: August 25, 2017

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在体外可编程的DNA裂变由真核阿尔戈诺特.

Guangbo Yan1, Xia Li1, Longyu Wang1

  • 1State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, Hubei 430062, China.

Nucleic acids research
|June 23, 2025
PubMed
概括

这项研究揭示了真核阿尔戈纳特 (eAgos) 可以切割DNA目标. CsAgo蛋白有效降解DNA和RNA,扩大了DNA操纵和基因沉默的应用.

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