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由单克隆抗体相互作用启发的小分子联素-23抑制剂的基于结构的选

Khac-Minh Thai1,2,3, Thi-Thanh-Thao Vu4, Quang-Minh Mai5,6,7

  • 1University of Health Sciences, Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Vietnam. thaikhacminh@gmail.com.

Molecular diversity
|June 23, 2025
PubMed
概括

研究人员确定了一种新的小分子抑制剂,r3-7,向介素-23 (IL-23) 治疗慢性炎症疾病. 这种具有成本效益的方法可以替代昂贵的抗体疗法.

关键词:
互乐金-23是什么意思分子对接是分子对接.分子动力学模拟模型单克隆抗体是一种单克隆抗体.制药学模型的建模.小分子抑制剂小分子抑制剂

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相关概念视频

Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...