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相关概念视频

Spectrophotometry: Introduction01:16

Spectrophotometry: Introduction

3.6K
Spectrophotometry is the quantitative measurement of the absorption, reflection, diffraction, or transmission of electromagnetic radiation through a material as a function of the intensity and wavelength of the radiation. A spectrophotometer is a device used to measure the change in the radiation intensity caused by its interaction with the material.
The essential components of a spectrophotometer include a source of electromagnetic radiation, a slot for placing a material to be analyzed, and a...
3.6K
UV–Vis Spectrometers01:14

UV–Vis Spectrometers

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The absorbance of UV and visible (UV–visible) radiations is measured using a UV–visible spectrophotometer. Deuterium lamps, which emit UV radiation, and tungsten lamps, which produce radiation in the visible region, are used as light sources in UV–visible spectrophotometers. A monochromator or prism is used for diffraction grating, i.e., to split the incoming radiation into different wavelengths. A system of slits is used to focus the desired wavelength on the sample cell.
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Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation

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Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
There are three main types of inductively coupled plasma atomic emission spectroscopy  (ICP-AES) instruments: sequential, simultaneous multichannel, and Fourier transform instruments, with the latter being less commonly used....
305
Atomic Absorption Spectroscopy: Instrumentation01:22

Atomic Absorption Spectroscopy: Instrumentation

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An atomic absorption spectrophotometer (AAS) comprises several components: a radiation source, an atomizer, a monochromator, and a detector. The radiation source can be a hollow-cathode lamp (HCL) or an electrodeless-discharge lamp (EDL), both of which provide a narrow emission line of the required wavelength. However, some instruments use continuum sources and high-resolution monochromators to achieve a narrow range of radiation.
The atomizer used in AAS can be either a flame atomizer or an...
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相关实验视频

Updated: Sep 18, 2025

Quantifying X-Ray Fluorescence Data Using MAPS
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建立定量SPECT成像测量的可追溯性

Andrew P Robinson1, Kelley M Ferreira2,3,4, Warda Heetun2,5

  • 1National Physical Laboratory, Hampton Road, London, TW11 0LW, UK. andrew.robinson@npl.co.uk.

EJNMMI physics
|June 23, 2025
PubMed
概括

建立定量单光子发射计算机断层扫描 (SPECT) 的测量可追溯性对于精确的分子放射治疗剂量测量至关重要. 这项研究展示了一种Lu SPECT的方法,达到1.6%的不确定性,并用器官幽灵验证它.

关键词:
测量不确定性 测量不确定性定量成像成像技术的使用.斯佩克特 (Spectre) 是一个运动场.可追溯性 可追溯性

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科学领域:

  • 医疗成像医学成像
  • 核医学是一种核医学.
  • 放射治疗 物理 物理

背景情况:

  • 定量单光子发射计算机断层扫描 (SPECT) 对分子放射治疗剂量测量至关重要.
  • 建立测量可追溯性对于数据协调和站点间比较至关重要.
  • 在所有校准阶段必须报告不确定性,以获得可靠的定量测量.

研究的目的:

  • 展示一个独立于制造商的方法来确定量化SPECT中的测量可追溯性.
  • 为了验证治疗放射性核酸的这种方法,Lu.
  • 展示使用标准临床设备建立可追溯性的局限性和能力.

主要方法:

  • 基于幻象的校准方法被用于定量Lu SPECT.
  • 使用校准的放射性核素校准器确定了可追溯性,并与人形器官幻影进行了验证.
  • 在整个校准链中进行了不确定性分析.

主要成果:

  • 主要的不确定性成分源于放射性核素校准器校准因子 (1.57%).
  • 最终的SPECT图像校准因子的不确定性为1.6%.
  • 在部分体积校正 (PVC) 的器官幻体中,脏和脏的活性恢复为96%~7%.

结论:

  • 展示了一种可复制的方法,用于在定量177 Lu SPECT 中建立测量可追溯性.
  • 使用标准临床设备成功建立了可追溯性.
  • 该研究强调了不确定性报告的重要性,以及PVC等修正的影响.