由hUC-MSC衍生的细胞外囊泡通过调节METTL3-介导的m6A修饰来保护肺组织免受香烟引起的损伤

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Jun Wen1,2,3, Jianwei Xu4, Ying Li5

  • 1School of Medical Sciences, Xiamen Medical College, Xiamen, People's Republic of China.

American journal of physiology. Cell physiology
|June 23, 2025
PubMed
概括

人类带介质干细胞衍生外细胞囊泡 (hUC-MSC-EVs) 通过METTL3.3恢复m6A修饰来保护肺细胞免受烟雾损伤. 针对METTL3-Wnt轴显示慢性阻塞性肺病 (COPD) 的治疗潜力.

关键词:
在METTL3中,METTL3是METTL3的第一个类型.在Wnt/β-catenin路径中.慢性阻塞性肺病 慢性阻塞性肺病由hUC-MSC衍生的细胞外囊泡.热致灭症是什么?

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