招聘和保留策略,以改善临床研究中的代表性:一个元综合
Carson J Peters1, Joan M Greve2, Arvin Karbasi3
1Department of Behavioral and Community Health, School of Public Health, University of Maryland, College Park, Maryland, United States of America.
PloS one
|June 23, 2025
概括
为了改善代表性不足的群体参与临床研究,战略必须侧重于社区赋权,信任和可持续性. 文化谦虚的方法和基于社区的参与性研究是有效招聘和保留的关键.
科学领域:
- 临床研究方法论临床研究方法论
- 健康差异研究 研究健康差异研究
- 社区对健康的参与.
背景情况:
- 慢性疾病不成比例地影响美国代表性不足的种族和少数民族群体.
- 临床研究在招募和留住多样化的参与者群体方面经常面临挑战.
- 需要创新策略来加强这些群体的纳入研究.
研究的目的:
- 确定基于证据的战略,以增加在慢性疾病临床研究中代表性不足的群体的招聘和保留.
- 综合对有效参与方法的定性研究的发现.
- 为未来的研究实践提供信息,以实现更大的包容性.
主要方法:
- 对定性研究的系统审查,重点是招聘和保留策略.
- 纳入标准指的是NIH定义的少数群体,美国主要的死亡/发病原因以及美国的研究.
- 对提取的数据进行主题分析,以确定关键主题和策略.
主要成果:
- 包括27项定性研究,主要侧重于癌症研究 (70%).
- 最常被引用的策略包括教育 (44%),沟通 (48%) 和基于社区的参与性研究 (CBPR) (63%).
- 从数据中出现的关键主题是授权,透明度,信任和可持续性.
结论:
- 有效的战略必须以社区为中心,可持续.
- 文化谦卑和基于社区的参与性研究 (CBPR) 是成功实施的基本要素.
- 优先考虑社区需求和建立信任对于增加参与慢性疾病研究至关重要.
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