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Updated: Sep 18, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

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代谢和免疫通路的POMC特异调节通过黑色皮质素-3受体信号传递

Mariya Nezhyva1, Friederike A Sandbaumhüter1, Per E Andrén1,2

  • 1Department of Pharmaceutical Biosciences, Uppsala University, 751 24 Uppsala, Sweden. erik.jansson@uu.se.

Molecular omics
|June 23, 2025
PubMed
概括

这项研究揭示了像ACTH,α-MSH和γ-MSH这样的黑色皮质-3受体 (MC3R) 激动剂如何影响细胞信号传递. 不同的激动剂独特地影响免疫和能量通路,为MC3R功能提供了新的见解.

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