在青少年异常性关节炎中对上肢的管理
Nicholas A Pulos1, Matthew L Basiaga, Marco Rizzo
1From the Division of Hand Surgery, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN (Pulos, Rizzo, and Feroe), and the Division of Pediatric Rheumatology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN (Basiaga).
概括
青少年异常性关节炎 (JIA) 是一种导致关节炎的儿童慢性疾病. 早期诊断和治疗对于维护功能和预防长期损伤至关重要.
科学领域:
- 儿科 儿科 儿科
- 类风湿病学 类风湿病学
- 整形外科 整形外科 整形外科
背景情况:
- 青春期异常性关节炎 (JIA) 是一种慢性炎症性疾病,影响16岁以下的儿童.
- 诊断依赖于临床检查,成像和亚型和预后的血清学测试.
- 早期干预是保持功能和骨生长的关键.
研究的目的:
- 审查有关JIA病理生理学,诊断和管理的当前文献.
- 专注于JIA的上肢参与.
- 强调手术管理的作用及其长期成果.
主要方法:
- 关于JIA病理生理学,诊断和治疗的文献综述.
- 分析当前的治疗策略,包括医疗和手术干预.
- 检查长期结果,特别是关于手术管理.
主要成果:
- 关节炎是一种异质的,终身的复发性疾病.
- 改变疾病的抗风湿药物显示出高缓解率 (>50%在1年内).
- 在骨成熟后考虑进行手术干预,但对于功能和损伤减轻至关重要.
结论:
- 联合评估要求采用多学科的方法来实现最佳管理.
- 需要进一步研究JIA中手术干预的长期结果.
- 有效的管理策略旨在尽量减少关节损伤并最大限度地发挥功能潜力.
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