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Updated: Sep 18, 2025

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扩散权重成像和易感权重成像在区分环增强的中枢神经系统原发性淋巴瘤从感染

Nutchawan Jittapiromsak¹, Phanuphong Sriinkua¹, Pornpattra Nimitpornsuko¹

¹Division of Diagnostic Radiology, Department of Radiology, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand.

The neuroradiology journal

|June 23, 2025

概括

扩散权重成像 (DWI) 和易感权重成像 (SWI) 可以帮助区分初级中枢神经系统淋巴瘤 (PCNSL) 和感染. 这些先进的MRI技术,特别是明显扩散系数 (ADC) 比率,在改善环增强大脑病变的诊断准确性方面表现有前途.

科学领域:

神经辐射学神经辐射学
神经瘤学神经瘤学
传染性疾病传染性疾病

背景情况:

从临床上来说,将环增强原发性中枢神经系统淋巴瘤 (PCNSL) 与感染区分开来是具有挑战性的.
准确的区分对于及时和适当治疗中枢神经系统病变至关重要.

研究的目的:

评估扩散权重成像 (DWI) 和易感权重成像 (SWI) 在区分环增强PCNSL和中枢神经系统感染方面的有效性.
评估定性和定量MRI特征的诊断性能.

主要方法:

在32名患者中对78个环增强性病变进行了回顾性审查.
限制扩散 (DWI) 和内损伤敏感性信号 (ISS) (SWI) 的定性评估.
使用明显扩散系数平均 (ADCavg) 和最小 (ADCmin) 的比率进行定量评估.

主要成果:

与感染相比,PCNSL的外周扩散显著受到限制,ISS阳性性更高.
与感染相比,PCNSL的外周和中心ADCavg和ADCmin比率明显较低.
周围ADCavg比率<1.25实现了高诊断准确度 (88.5%) 来区分PCNSL和感染.

结论:

在DWI上限制传播和在SWI上积极的ISS是PCNSL的有价值指标.
测量ADC比率为区分PCNSL和中枢神经系统感染提供了重要的辅助信息.
这些先进的MRI技术增强了复杂环增强大脑病变的诊断能力.

关键词:

主要中枢神经系统淋巴瘤表面扩散系数的明显扩散系数扩散权重成像技术的使用.环增强的病变是指环增强的病变.敏感度加权的成像成像方法

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