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来自Streptomyces flaveolus的未描述的ansatrienin类似物,包括两个N-乙半氨酸合物

Xiaofan Zhu1, Xiaomei Wu2, Hongji Li1

  • 1School of Pharmacy, Naval Medical University, 325 Guohe Road, Shanghai, 200433, China.

Phytochemistry
|June 23, 2025
PubMed
概括

在Streptomyces flaveolus中发现了五种新的ansatrienin类似物. 三胺素N显示出强烈的细胞毒性活性,而C-25氧化和N-乙半氨酸附着等修改降低了有效性.

关键词:
安萨米辛是一种安萨米辛.一个三角形在内.细胞毒性 细胞毒性N-乙半氨酸的结合物这种植物是Streptomyces flaveolus.链杆菌植物家族 (Streptomycetaceae) 的一个家族.

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