在诊断上肢软组织感染时使用急性相反应剂
John A Buchan1, Andrew Burkhart2, Phillip R Ross2
1Department of Orthopaedic Surgery, University of Cincinnati College of Medicine, 231 Albert Sabin Way, OH, 45267, Cincinnati, USA. buchanj5@ucmail.uc.edu.
International journal of emergency medicine
|June 23, 2025
概括
像CRP,ESR和WBC这样的急性相反应剂对于诊断上肢感染,尤其是手腕远部感染,是不可靠的. 临床评估对于有效的治疗决策至关重要.
科学领域:
- 紧急医疗 紧急医疗
- 传染性疾病 传染性疾病
- 手术感染 手术感染
背景情况:
- 上肢软组织感染在急诊室很常见,需要及时治疗.
- 急性相反应物,包括C反应蛋白 (CRP),红细胞沉积率 (ESR) 和白细胞计数 (WBC),经常用于诊断.
- 这些生物标志物对上肢感染的诊断实用性需要进一步评估.
研究的目的:
- 评估急性相反应剂 (CRP,ESR,WBC) 在需要干预的上肢感染患者的诊断价值.
- 确定这些生物标志物的可靠性,特别是在距离手腕的感染.
主要方法:
- 在5年的时间里,对103名患上上肢感染需要切口和排水的患者进行了回顾性审查.
- 分析实验室值,包括ESR,CRP和WBC计数.
- 生物标志物水平与感染位置和培养结果的相关性.
主要成果:
- 急性相反应剂表现出可变的灵敏度和可靠性,特别是在距离手腕的感染中.
- 平均ESR为42毫米/小时,CRP为64.1毫克/升,WBC为10.5 × 103/μL.
- 所有患有正常急性相反应物的患者都有手腕或手腕的远部感染;培养负的病例在实验室值中没有显著差异.
结论:
- 急性相反应剂在诊断上肢感染方面存在局限性,特别是那些距离手腕的感染.
- 这些生物标志物不应该是疑似感染的管理决策的唯一依据.
- 临床检查和病史对于指导上肢感染的治疗至关重要.
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