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在可行性研究中的样本大小证明:超越已公布的指导方针.
1Department of Biostatistics and Data Science, University of Kansas Medical Center, 3901 Rainbow Blvd., Kansas City, 66160, KS, USA. rmontgomery@kumc.edu.
Pilot and feasibility studies
|June 23, 2025
概括
试点和可行性研究需要更好的样本大小证明. 将它们基于操作特征,确保在未来的临床试验中做出可靠的决定.
科学领域:
- 临床试验方法论 临床试验方法论
- 生物统计学 生物统计学
- 研究设计研究研究设计
背景情况:
- 试点和可行性研究对于为后续更大规模的随机对照试验做决定提供信息至关重要.
- 目前对可行性研究的样本大小证明通常依赖于务实的理由或经验规则,缺乏统计的严谨性.
- 对于这些初步研究,需要更明确的最佳实践来确定样本大小.
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