在化单心室循环中自发血的30年流行率
Anna K Dibbs1, Liyun Zhang2, Amy Y Pan2
1Department of Pediatrics, Division of Cardiology Medical College of Wisconsin, Children's Wisconsin, Herma Heart Institute Milwaukee WI USA.
Journal of the American Heart Association
|June 24, 2025
概括
自发血发生在3.4%的单心室循环息患者中. 在超过一半的受影响个体中观察到复发,突出显示需要持续监测.
科学领域:
- 心脏病学 心脏病学
- 儿童心脏病学 儿童心脏病学
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 自发血栓塞是单心室循环息的已知并发症.
- 现有的文献主要由病例报告和小系列组成,限制了对长期患病率的理解.
- 这项研究解决了对这种患者群体中血病发病率和结果的数据需求.
研究的目的:
- 为了确定患者中自发血栓塞的长期患病率,息单心室循环.
- 描述与自发血栓塞相关的临床结果和复发率.
- 为了提供一个全面的分析,在一个大队列的血,单心室生理学.
主要方法:
- 追溯性研究设计,包括从1990年到2023年接受格伦或方坦息治疗的患者.
- 使用ICD-9和ICD-10代码进行"肺出血"和"血"进行初始查.
- 手动图表审查证实了血发作和患者分类.
主要成果:
- 总共分析了799名患者,其中3.4% (27/799) 被诊断为自发血栓塞.
- 在27名患者中发生了61次血栓塞,其中83.6%发生在Fontan息后.
- 超过一半的血栓塞患者 (51.9%) 经历了复发,复发的中位时间为0.6年.
结论:
- 这项研究首次量化了在一大群化单心室患者中血病发病率.
- 发现自发血栓塞的总体患病率很低,为3.4%.
- 发现复发率很高 (51.9%),强调了这种并发症的慢性性质.
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