在心声谱推队列中,右心室功能障碍的发生率
Jonah D Garry1, Shi Huang2, Jeffrey Annis2
1Division of Cardiovascular Medicine Vanderbilt University Medical Center Nashville TN USA.
Journal of the American Heart Association
|June 24, 2025
概括
右心室功能障碍 (RVD) 在接受心声图的患者中很常见. 事件RVD显著增加心力衰竭住院的风险,突出显示需要监测.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏衰竭研究研究
背景情况:
- 右心室功能障碍 (RVD) 的发生率尚未确立.
- 以前的研究还没有充分探讨与RVD和右心室肺动脉 (RV-PA) 分离相关的风险因素和心力衰竭 (HF) 住院危险.
研究的目的:
- 为了确定RVD和RV-PA脱的发生率.
- 确定与事件RVD和RV-PA脱相关的风险因素.
- 评估发生RVD或RV-PA脱的患者中HF住院的危险性.
主要方法:
- 追溯队列研究,使用2010-2023年间的跨胸腔心声图 (TTE) 数据.
- 随访的患者基线右心室功能正常 (三环状平面缩外流[TAPSE]≥17毫米).
- 评估了新的RVD (TAPSE<17 mm) 和RV-PA解 (TAPSE/右心室缩压[RVSP]<0.36 mm/mm Hg),使用了发病率和Cox模型进行分析.
主要成果:
- 确定了45,753名患者;RVD和RV-PA脱的发病率分别为8.2和3.4人/年.
- 与较高的RVSP.观察到的发病率增加. 脑膜炎和心房动是主要的危险因素.
- 事件RVD (HR,2.02) 和TAPSE下降≥5毫米显著增加HF住院危险.
结论:
- 在TTE转诊的患者中观察到大量的RVD发病率.
- 建议对RVSP>35mmHg进行临床监测.
- 心血管并发症是RVD和RV-PA脱的关键驱动因素,事件RVD与更高的HF住院风险有关.
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