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Updated: Sep 18, 2025

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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了解PFAS吸收,分布和消除的机制,使用一种基于生理学的毒动力学模型

Fabian C Fischer1,2, Colin Thackray1, Nicholas Ferguson2

  • 1Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, United States.

Environmental science & technology
|June 24, 2025
PubMed
概括

一个新的基于生理学的毒性动力学 (PBTK) 模型有助于了解和多基物质 (PFAS) 如何在体内移动. 该模型揭示了影响小鼠PFAS吸收,分布和消除的关键因素.

关键词:
在PFAS中,我们可以使用PFAS.淘汰 淘汰 淘汰 淘汰鼠标模型 鼠标模型鼠标模型组织分布 组织分布毒动力学建模 毒动力学建模

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