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没有经过验证的非结核菌菌的亚急性乳腺炎仍然是一个临床挑战
Lara Kakabas1,2, Anna Granath1,2, Kaijsa Edholm3
1Division of Otorhinolaryngology, Department of Clinical Science, Intervention and Technology Karolinska Institutet Stockholm Sweden.
Laryngoscope investigative otolaryngology
|June 24, 2025
概括
儿童的亚急性乳腺炎 (SAM),通常与非结核性菌根菌 (NTM) 相关,需要通过成像和活检及时诊断. 建议与长期抗菌素治疗相结合的手术干预,以获得最佳的结果.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 儿童传染病 儿童传染病
- 微生物学 微生物学
背景情况:
- 亚急性乳腺炎 (SAM) 是一种惰的感染,带来了诊断和治疗方面的挑战.
- 在SAM和非结核菌菌 (NTM) 感染之间存在潜在的联系.
- 侵略性的骨破坏和并发症需要进一步调查SAM.
研究的目的:
- 调查儿科亚急性乳腺炎 (SAM) 的临床特征.
- 为了确定SAM的最佳治疗策略.
- 分析儿科SAM病例的结果和并发症.
主要方法:
- 从2003年到2023年,对儿童患者 (0-17岁) 进行回顾性调查,这些患者因SAM住院治疗.
- 数据收集包括人口统计,诊断 (放射学,微生物学,组织病理学),治疗和临床结果.
- 在瑞典卡罗林斯卡大学医院对16例儿科病例的分析.
主要成果:
- 确定了16例儿童SAM病例,中位数年龄为7.5岁.
- 在6例病例中检测到非结核性真菌菌 (NTM) 感染.
- 大多数病例涉及长期的耳鼻,CT上骨破坏,在组织病理学上颗粒状炎症;七例病例有延迟恢复或复发.
结论:
- 组织病理学和微生物学采样,以及CT扫描,对于诊断SAM至关重要.
- 建议与经验长期抗菌素治疗相结合的手术干预,以获得最佳的恢复.
- 早期诊断和有针对性的治疗对于管理儿科SAM和预防并发症至关重要.
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