对传统香烟和电子香烟使用者口腔粘膜细胞学变化的比较分析
Magdi M Salih1, Thamer A Tamr2, Tariq E Elmissbah1
1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif City, Kingdom of Saudi Arabia.
Tobacco induced diseases
|June 24, 2025
概括
无论是传统的还是电子的吸烟,都会显著改变口腔细胞. 长期和大量吸烟加剧了这些口腔粘膜变化,强调了尼古丁产品的细胞毒性作用.
科学领域:
- 口腔病理学 口腔病理学
- 细胞生物学 细胞生物学
- 公共卫生 公共卫生
背景情况:
- 口腔粘膜细胞学变化是吸烟者关注的一个问题.
- 传统和电子烟的使用呈现出不同的暴露特征.
研究的目的:
- 为了比较传统香烟吸烟者与电子香烟吸烟者的口腔粘膜中的细胞学变化.
- 评估吸烟习惯对口腔细胞形态学的影响.
主要方法:
- 一项涉及159名参与者的横截面研究 (97名吸烟者,62名非吸烟者).
- 用帕帕尼科劳染色法收集和分析的口腔涂抹.
- 从塔伊夫大学的学生和工作人员中招募的参与者.
主要成果:
- 吸烟者 (46.4%) 的反应性和炎症性变化比非吸烟者 (3.2%) 更为普遍.
- 传统香烟使用者比电子香烟使用者 (37.5%) 的变化率更高 (51.4%).
- 吸烟持续时间≥5年与显著更高的细胞学变化相关 (71.8%).
结论:
- 吸烟和口腔粘膜细胞形态变化之间存在强烈的关联.
- 吸烟的强度和持续时间显著影响这些细胞变化的严重程度.
- 这些发现强调了吸烟对口腔细胞的细胞毒性影响,需要进行公共卫生干预.
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